体细胞治疗用CD3单克隆抗体 | ||||||
品牌 | Code No. | 产品名称 | 包装量 | 价格(元) | 说明书 | 数量 |
Takara | T210 | Anti-CD3 mAb GMP grade,Anti-CD3 monoclonal antibody (Clone OKT3) | 1 ml | ¥7,138 |
体细胞治疗用CD3单克隆抗体 | ||||||||||
|
||||||||||
Anti-CD3 antibody is used in proliferating T lymphocytes. Among many clones, the clone "OKT3" is most popularly used. Anti-CD3 mAb GMP grade is manufactured as a quality- assured product, according to guidelines for Good Manufacturing Practice (GMP) for Investigational Products. No animal- or human- derived components were used for manufacture of this product. This product can be used for ex vivo cell culture processing and is limited to investigational use only. · GMP grade anti-CD3 monoclonal antibody (clone; OKT3) · To be used in T lymphocyte proliferation · No animal- or human- derived components were used for manufacture of this product · For research use and ex vivo cell culture processing only |
||||||||||
[Product] | ||||||||||
anti-CD3 monoclonal antibody Clone" OKT3"( isotype: mouse lgG2a) |
||||||||||
[Size] | ||||||||||
1.0mg protein/1.0ml in a 2ml cryovial |
||||||||||
[Storage Buffer] | ||||||||||
Phosphate- buffered?saline( PBS), pH7.4, with 200 ppm polysorbate 80. |
||||||||||
[Quality] | ||||||||||
- With the exception of mouse hybridoma cells, we do not use any human- or animal-derived materials during the production of Anti-CD3 mAB GMP grade. - Endotoxin; <5 EU/ml as determined by kinetic Limulus Amebocyte Lysate (LAL) assay. - Manufactured according to relevant GMP guidelines. |
||||||||||
[Shipping and Storage] | ||||||||||
Shipping at -80℃ Store at or below -70℃ |
||||||||||
[Application 1] | ||||||||||
CIK ( Cytokine- induced Killer) cells expansion by stimulation with Anti-CD3 mAb GMP grade and cytokine. |
||||||||||
PBMCs were stimulated with Anti-CD3 mAb GMP grade, IFN-γ, IL-1α and IL-2 for 5 days. After stimulation, activated lymphocyte were diluted with medium and cultivated for 9 days. Figure shows expansion fold on day 5,7,9,12 and 14. |
||||||||||
[Application 2] | ||||||||||
Co-stimulatory effect of Anti-CD3 mAb GMP grade and Retronectin in T-lymphocyte expansion. |
||||||||||
PBMCs were stimulated with pre-coated Anti- CD3 mAb GMP grade or pre- coated Anti- CD3 mAb GMP grade and Retronectin for 4 days. After stimulation, activated lymphocyte were diluted with GT-T551 medium and cultivated. Figure shows expansion fold on day10. |
||||||||||
文件下载: 《体细胞治疗用CD3单克隆抗体》 |
||||||||||
页面更新:2024-02-20 16:19:52