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Stem121
品牌 Code No. 产品名称 包装量 价格(元) 说明书 数量
Cellartis Y40410 STEM121® 50 μg ¥1,871
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Stem121:
抗人类细胞质蛋白的小鼠抗体(mouse Ab against a protein in cytoplasm of human cell)
 
Isotype: IgG1
Form: Unconjugated
在小鼠脑部海马体中,使用Stem121检测到移植进入的人类神经干细胞的迁移和分化。 在小鼠肝脏中,使用STEM121检测到移植进入的人类肝脏移植细胞 (hLEC)。
 
反应特性:
STEM121特异性地与人类细胞细胞质中的某个蛋白反应,该抗体在人类脑组织、肝脏组织、胰腺组织中都有表达。 其中,该抗体在中枢神经细胞出现最高水平的表达。该抗体与小鼠、大鼠、猴子的脑组织或其他组织提取物无交叉反应。
 
产品储藏:
STEM121是从小鼠腹水获取并采用Protein A亲和纯化。
本产品溶解于含有0.02 % NaN3的PBS(pH 7.4)中。
本产品在2 - 8℃中保存。
 
产品应用:
STEM121应用于检测被移植进入小鼠、大鼠等动物体内的人类细胞的移植、迁移、分化情况。本抗体可以检测被移植的人类细胞的位置,可以用来评估被移植细胞的数量,还可以用来监控被移植细胞的形态(进行免疫组化检测时, 通常1:1,000稀释;进行免疫荧光检测时,通常1:500稀释)1, 2, 3, 4, 5。我们建议用户自行摸索合适的本抗体产品的实验条件。
 
■ 产品详情请点击:
 
重要提示:
This product is for research use only(本产品只用于研究用途). It is not intended for use in therapeutic or diagnostic procedures for humans or animals. Also, do not use this product as food, cosmetic, or household item, etc. Takara products may not be resold or transferred, modified for resale or transfer, or used to manufacture commercial products without written approval from TAKARA BIO INC. If you require licenses for other use, please contact us by phone at +81 77 565 6973 or from our website at www.takara-bio.com. Your use of this product is also subject to compliance with any applicable licensing requirements described on the product web page. It is your responsibility to review, understand and adhere to any restrictions imposed by such statements. All trademarks are the property of their respective owners. Certain trademarks may not be registered in all jurisdictions.
 
参考文献:
1. Kelly S, et al. (2004) Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. PNAS. 101: 11839- 11844.
2. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS. 102: 14069-14074.
3. Tamaki SJ, et al. (2009) Neuroprotection of host cells by human central nervous system stem cells in a mouse model of infantile neuronal ceroid lipofuscinosis. Cell Stem Cell. 5: 310-319.
4. Kallur T, et al. (2006) Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats. J Neurosci Res . 84: 1630-1644.
5. Salazar DL, et al. (2010) Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model. PLoS ONE. 5: e12272.