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Engrafted Cell Markers
品牌 Code No. 产品名称 包装量 价格(元) 说明书 数量
Cellartis Y40400 STEM101® 50 μg ¥1,871
Cellartis Y40410 STEM121® 50 μg ¥1,871
Cellartis Y40420 STEM123® 50 μg ¥1,871
监控人类细胞移植用途的抗体
(Antibodies for Detecting Human Cells Transplanted into Mice and Rats)
STEM101、STEM121、STEM123是三种小鼠来源的单克隆抗体,用于人类细胞向小鼠和大鼠移植实验中,监控细胞移植、转移、分化。
 
■ 产品特点
· STEM101 reacts specifically with the nuclear human Ku80 protein; the antibody does not cross-react with mouse or rat Ku80 in brain tissue or cell extracts
Note: STEM101 (Y40400) is not suitable for immunohistochemically staining on paraffin embedded tissue sections. We recommend using fresh frozen tissue with this antibody.
· STEM121 reacts with a human cytoplasmic protein expressed in brain, liver, pancreas, and CNS cells the antibody does not cross-react with brain tissue or cell extracts from mouse, rat, or cynomologous monkey
· STEM123 reacts specifically with human GFAP, a marker of astroglial cells; the antibody does not cross-react with brain tissue or cell extracts from mouse or rat
 
■ 产品应用
· Localization, quantification, and/or characterization of engrafted cells of human origin by immunohistochemistry and immunofluorescence
 
 
 
■ 产品详情请点击:
 
STEM101 detects nuclei of transplanted human neural stem cells in the olfactory bulb of a mouse brain.
 
STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.
 
STEM123 detects human GFAP+ astrocytes differentiated from human neural stem cells after transplantation into a mouse brain.
 
参考文献:
1. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074.
2. Guzman R, et al. (2007) Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. PNAS 104: 10211-10216.
3. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319.
4. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5: e12272.
5. Kelly S, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. PNAS (2004) 101:11839 11844.
6. Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074.
7. Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319.
8. Kallur T, et al. Human Fetal Cortical and Striatal Neural Stem Cells Generate Region-Specific Neurons In Vitro and Differentiate Extensively to Neurons After Intrastriatal Transplantation in Neonatal Rats. J Neurosci Res. (2006) 84:1630-1644.
9. Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5: e12272.
10. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319.
11. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5:e12272.
12. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074.